summation: According to a major study of more than 1.6 million women, if your sister has experienced this condition, it is more than 10 times more likely to cause postpartum psychosis. This rare but serious disorder, marked with hallucinations, paranoia and disorder after childbirth, can result in life threats without treatment.
This result is especially emphasizing the need for early screening and perception, especially when there is a bipolar disorder. Although the relative risk is high, but the actual risk is 1.6%, it is possible to understand the family history, but if you understand your family history, you can aim for preventive mediation and mental health during postpartum vulnerable postpartum.
Main fact:
- High family risk: Sisters with postpartum psychosis have more than 10 times the risk of women.
- Both polar link: If the sister has a bipolar disorder, the risk increases by 14 times.
- Recognition request: Despite its severity, postpartum psychosis still remains under diagnosis.
source: Mount Sinai Hospital
Sinai Mount researchers found that for the first time a woman experienced a sister, she was more than 10 times more likely to cause postpartum psychosis.
The result published on May 19 American psychiatric journal On the same day, we propose the effects of genes and shared environments emphasized in the media briefing of the annual meeting of American Psychiatric Association.
Postpartum psychosis is rare, but it has a serious mental illness with a fatal influence on the vulnerable state and for several months after childbirth. Leaving it without treatment increases the risk of suicide and infant murder.
Among the initial warnings of postpartum psychosis are serious changes, hallucinations, disorders, insomnia, paranoids and self -harm.
Despite the disruptive ripple effect of the disability, it still remains scientifically and is a challenge for a doctor to diagnose and solve.
“All women and doctors of childbirth age need to know about postpartum psychosis, seriousness, symptoms, and family risks, so they can be diagnosed and prevented quickly.
“At present, high -risk women are leaving too many women to leave alone without knowing it, and we hope that these findings will help to move the needle and reduce change.
“With a wider perception of these specific conditions and risk factors, we can implement change to alleviate the burden of women during this postpartum.”
The Mount Sinai research team surveyed more than 1.6 million women’s records of Swedish registered agencies and confirmed 2,514 women who experienced postpartum psychosis within three months of their first birth.
Not only do you find that a woman is more than 10 times more likely to cause postpartum psychosis if she has a condition, but also a study of Swedish registry has doubled the risk of postpartum psychosis.
Women with sisters with bipolar disorders and postpartum psychosis were the most risk. The risk of postpartum psychosis itself increases 14 times.
This study measures the relative recurrence risk of disability, which means increasing the possibility of appearing in other family members. This is different from the actual risk. This indicates the probability of developing conditions.
The researchers found that the relative risk of postpartum psychosis is that the official brothers and sisters are quite high, but the absolute risk of women with affected sisters is still low.
Dr. Bergink said, “This discovery supports the view that there is a duplicate between postpartum psychosis and bipolar disorders, but in reality it is a clear condition.
“We hope that this new data will help you move the needle and reduce the change. We need to take measures to help ease the burden of women during this postpartum, recognizing these specific conditions and danger elements.”
In addition to expanding the perception of postpartum psychosis, this study provides a solid foundation for the next research stage with the goal of initial perception and prevention.
The work of identifying the genes in charge of this disease is already in progress in the SINAI in the laboratory of the psychiatric and assistant professor of ICAHN School of Medicine.
Dr. Mahjani said, “We are using complex molecular data to investigate the genetic structure of the disease.
“Even if certain genes are involved in the mechanism and trigger of postpartum psychosis, and hormones or immune -related, we can lead us to new treatments and women in advance before facing a serious health crisis.”
About these postpartum psychosis and genetics research news
author: Elizabeth Daul Ring
source: Mount Sinai Hospital
Contact: Elizabeth Daul Ring -Mount Sinai Hospital
video: Images are recognized as neurological science news
Original study: Open access.
“Family risk of postpartum psychosis“By Veerle Bergink. American psychiatric journal
Abstract
Family risk of postpartum psychosis
purpose:
Postpartum psychosis is one of the most serious psychiatric conditions, and if it is not processed, there is a high risk of suicide and infant. Genetic factors contribute to the risk of postpartum psychosis, but the degree of family risk must still be determined.
The author hypothesized in the type of other family relations that the risk of relative recurrence was compared to the relative relative relative risk of postpartum psychosis depending on the degree of genetic relevance and higher in the entire female sisters than cousin.
methods:
The cohort study consisted of 1,648,759 women of Sweden’s national registration, and 2,514 (0.15%) experienced postpartum psychosis within three months after the first birth. The authors estimated the risk of relative recurrence of postpartum psychiatric diseases against female sisters and cousins as a measure of family risks.
result:
The risk of relative recurrence of postpartum psychosis in all brothers and sisters was 10.69 (95% CI = 6.60, 16.26) when adjusted to birth year and age. Although the cousin had a relative risk of relative recurrence, these results did not reach statistical significance (1.78, 95% CI = 0.70, 3.62).
Despite the high risk of postpartum psychosis among the complete brothers and sisters, the absolute risk of women affected by the brother was relatively low and was estimated to be 1.60%within the total population.
conclusion :
In the complete brothers and sisters, the increased risk of postpartum psychosis suggests the impact of genes and shared environments. But significant results of Cousins interfere with the exact difference between these factors.
In addition, despite the increase in the risk of relative recurrence of brothers and sisters, the possibility of developing postpartum psychosis is still low.
This study emphasizes that further research is needed to better understand the complex interactions of genetics and sharing environments in the development of postpartum psychosis.
