dAnielle Griffin grew up as a self -proclaimed “Chengki Ai” and was harassed by weight, always hungry and suffered from confidence.
So she finally felt the answer she always dreamed of when she knew that celebrities were suddenly shedding dozens of pounds using new diabetes and weight loss drugs. She went online and received an Ozempic prescription, waiting for her life and body to change.
Griffin seems to be one of the estimated things 20 % Of those who do not succeed in GLP-1 drugs.
Griffin said, “It was a new craze. Everyone had a surprising result and I was not.” independence.
She was stagnant after she lost a small amount of initial weight (13 pounds) for the first two months. A few months have passed, and the scales have not changed. Griffin felt that she failed to lose weight.
More than two out of five American adults are obese. Chronic diseases are diversified and doctors say it is not uncommon for patients not to lose weight of GLP-1 drugs. A recent study by the University of Pennsylvania found that 35-50 % of patients do not lose more than 5 % of their weight.
It means that there are many people who do not get the results they expect. Dr. Mark Vessleler, a surgical chairman and obesity expert at Northwell Lenox Hill Hospital, New York, said, “We need to change the approach instead of treating obesity as if we were treating cancer 70 years ago.

“This is, ‘Oh, it is a disease, it may appear in another organs, but one disease.’ We no longer treat cancer with a separate understanding of cells involved in chemotherapy that can react with natural history. ” “We still see obesity as follows: It’s a disease. It’s almost definitely a disease.”
Griffin, a 38 -year -old information technology manager from New Mexico, moved to WEGOVY, another semi -glucided drug, which helps to control the body’s blood sugar levels because the drug was more widely available after the ozempic started.
Her initial weight loss gained her hope: “Oh, this is amazing. It will work.” “And then nothing has been lost.”

Despite her lack of major results, she was told that she could not escape the drug.
Griffin said, “I am disappointed to see all the success stories and see people.”
She wiped the message board to read the experience of others. She did not feel any side effects from the drug. Pancreatitis and vomiting But those who seem to lose their weight are those who lose the greatest weight, she said.
But doctors point out that it is never clear what patients will succeed in the drug. Bessler said, “I don’t know who will respond, not respondents, and how many people will lose.
Dr. Michael Knight, an associate professor and obesity doctor at George Washington University. He said in his experience that some people were better success in Zepbound than other drugs because they were double agents. GIP and GLP-1 hormoneOzempic only stimulates GLP-1.
“Some people have excessive weight due to drugs. Others can handle the food they eat. Others may have an insulin resistance, or there may be other metabolic conditions that affect the way the body is managed,” Knight said. “As a result, one treatment will work differently for those who can expect weight loss.”

Those who take ozempic and similar drugs usually lose 15-20 %of their weight. Columbia University Irving Medical Center. About 10 -third of the patient experiences about 10 %of weight loss.
Despite concerns about potential side effects and effects About 30 million Americans We have tested the drugs, including the drug producer Novo Nordisk’s Wegovy and Ozempic, ELI Lilly and Company Mounjaro and Zepbound. Originally, weight loss drugs for treating diabetes are imitated by imitating natural hormones that can suppress the user’s appetite. However, as the popularity increased, the patients were lacking.
Kyle Smith, a 37 -year -old Kyle Smith, owns an IT consulting firm in southern California, said he led the drug to test the drug after seeing how much weight was lost. It was regarded as obesity, but there was no pre -conditions such as diabetes or heart disease. His doctor was boarded to take Wegovy, but his insurance would not deal with it. He began to pay drug costs at pharmacies other than the United States and cut two -thirds of the cost. Like Griffin, he got an accessible drug and lost 40 pounds.
But side effects were overwhelming. Smith was tired and suffered from heart burns and constipation. He decided to get off the drug, but immediately he began to gain weight “too fast.”

Now Smith is back to Wegovy.
“I don’t think it is trying to lose weight for the first time. “I have been doing it for two months now, and I think I’ve lost 6-7 pounds. This is definitely slower than before.”
Griffin said he was gaining weight after taking the medicine for several weeks. She said she should know that everyone is different.
“It can be very isolated, and others are successful in the drug, there are many stigma around them, how popular it is, and it is not effective for anyone,” she added. “You feel ‘what’s the problem with me?’
The weight loss drug is just one option. Many people are not successful.
Knight said, “Not all sizes are right.