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Maternal diabetes, a complication of pregnancy that can affect 1/3 Women around the world Big new study Established
This study, published in the Lancet Diabetes & Antocrinology Journal on Monday, is increasingly evident that tie maternal diabetes into various health complications for two things. mother and children. The result is only correlation, but experts said they emphasized the need for screening and early treatment of diabetes, which are more common in data.
It is estimated in the United States 10 % of women I was diagnosed with diabetes in 2021 9 % Among pregnant American women, pregnancy diabetes occurs every year.
Dr. Elizabeth HalPrin, an adult diabetes director of Joslin Diabetes Center, said, “We have known that there is a little association between the rising glucose level of pregnancy and the future neurological disorders for a while, and Boston in Boston Dr. Elizabeth Hal, the director of adult diabetes at Joshlein Diabetes, said that the new discovery was not involved in this study.
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In 202 studies of more than 55 million pregnancy worldwide, analysis of data collected data was examined for children who had type 1 or type 2 diabetes during pregnancy or diagnosed with pregnancy diabetes. These conditions are comprehensively called “maternal diabetes”.
Even if the study describes other factors such as the age or body mass index of the woman, children born in women with diabetes during pregnancy were 28 % more likely to cause nerve development problems than children without disease. The risk of ADHD and intellectual disorders was slightly higher than the risk of other problems, such as autism.
This analysis was more likely to be nervous disorders in children with diabetes before pregnancy compared to diabetic patients before pregnancy.
The risk has increased even if gestational diabetes is more severe to guarantee drugs for longer periods of time, or for a serious guarantee of drugs.
Fangkun Liu, the author of this paper and the neurosurgery associate professor of Central South University in Changsha, is surprisingly consistent with how large and diverse the data set was.
It is not clear what is behind the potential connection between hyperglycemia and nerve development problems. The author of this study suggests that type 1 diabetes, which is immune, can increase inflammation of children in relation to the increase in autism and the risk of ADHD. Maternal diabetes also affects how genes are expressed and can cause changes that affect brain function, they said.
Doctors also know for many years that hyperglycemia increases the risk of neurological congenital defects, including the state of spine and antencephaly without the brain completely developed. Therefore, Dr. Susan Spratt, a professor of endocrine at Duke University Medical School, is not surprising that hyperglycemia can also affect other types of nervous system development.
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Dr. LIU said the study does not establish diabetes as a direct cause of neurological disorders. Some studies on analysis examined their brothers and sisters and found no clear connection between maternal diabetes and nerve development.
Dr. HalPrin and the author pointed out that new studies did not include much data from low -income countries, such as the southeastern and Southeast Asia, where maternal diabetes spread more.
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The biggest question that did not answer is whether or not to control blood sugar can reduce this potential risk.
Dr. Kartik Venkatesh, director of the diabetes director of OHIO State University, said, “As a doctor of this space, a doctor of this space, I want to know more about the effects of glucose control during pregnancy, and the authors demanded more strict research on this question.
Some experts say that this study pointed out that a comprehensive diabetes screening is needed among young women in their 20s and 30s, so anyone who can be pregnant is treated before thinking. About 4 %of American women had diabetes that had not been diagnosed in 2021.
The American Diabetes Association encourages women with diabetes to meet with maternal-fetal medical professionals when planning endocrine scholars or pregnancy. In addition to controlling blood sugar before pregnancy and during pregnancy, some patients are known to cross the placenta and may be commonly discontinued to take certain drugs such as drugs called Sulfonyluras, which is not recommended during pregnancy. There are few studies on the effects of drugs such as ozempic during pregnancy.
ADA recommends that diabetic patients will receive nutritional counseling that promotes grain, lean protein and fresh fruits and vegetables. Exercise can help to improve glucose levels and reduce the need for insulin, a drug preferred for diabetes during pregnancy.
Dr. Venkatesh said, “This discovery may be seen,” he said. “The reality of diabetes treatment during pregnancy is that we have a treatment.”
