The United States has had some changes in the US and domestic policies since President Donald Trump took office in January. Scientists who rely on federal subsidies for their work were particularly difficult to have new regulations and cuts.
Already, researchers in various fields, including LGBTQ+ health and gender identity, climate and environment and medical research, have raised research funds.
Recently, studies on vaccine hesitations have suffered this fate. According to some media in the United States, more than 30 subsidies have been terminated to study the public’s distrust of vaccination.
Among these cuts, the role of Robert F. Kennedy Jr.
According to KFF Health NewsNIH (National Institute of Health) director Matthew Memoli provided Kennedy and the White House for details of “subsidies, contracts or cooperation” for MRNA vaccine research.
Similar requests are reported before the administration’s decision to discard support for vaccine hesitation research.
Researchers, who talked about anonymity, also told the media that NIH officials advised to eliminate MRNA reference in the subsidy application.
However, since technology is currently at the forefront of medical development, it will result in extensive results if you stop MRNA research.
MRNA, the basis of two coved vaccines
The biggest argument for the reputation of MRNA technology is the basis of the Covid-19 vaccine created by BionTech-Pfizer and Moderna within a year of the corona virus epidemic. The researchers behind this technology also won the Nobel Prize in Medicine.
As with many other vaccines, instead of using a disabled version of the virus, Astrazeneca’s first launch covid jaw (BionTech-PFIZER and MODERNA shots include mRNA or messenger RNA.
MRNA is a gene molecule that occurs in multi -cell organisms, including plants, animals and mold. It acts as a genetic script. It provides a template for producing proteins that are specified and protein that performs essential functions.
Covid vaccines containing mRNA scripts allow body cells to produce the same protein as spike protein on the external shell of corona virus. This means that the immune system of a person who has been vaccinated has a goal to identify and immediately attack pathogens when infection.
This vaccine is very effective in preventing serious symptoms and can save a lot of life.
The claim that the conspiracy theorists changed the DNA of the beneficiaries, claiming that many people distrusted the vaccine. The mRNA vaccine is not grounded because our main genetic information does not enter the nucleus of the cells stored.
Malaria MRNA vaccine in the current developmental rimbo
The only malaria vaccine in use as “RTS, S” or “MOSQUIRIX” is not a MRNA shot.
But MRNA -based malaria vaccines are being developed. They can help fight mosquito -mediated diseases that kill about 600,000 people every year, two -thirds of them are children under five years of age.
2023, A New Zealand and Australian research teams said they developed MRNA shots. It succeeded in the animal model. The vaccine stimulates immune cells in the liver, where the malaria manufactured plasmodium parasites enter the bloodstream and move.
Of course, it is a big leap into human medical exams and vaccines in animal models. The process can take several years.
Nevertheless, experts believe that the MRNA vaccine is especially suitable for dealing with malaria because it can be adjusted quickly in the case of mutations of the disease. It is also a plus of the MRNA flu vaccine currently being developed.
The German pharmaceutical company BionTech operates two and two tests on the first stage and its own MRNA malaria vaccine, which has been tested by humans. But as of March 5, 2025, this is the case. Stop by the US Food and Drug Administration (FDA)Where the test took place.
BionTech has requested a change and is working with the FDA to solve the request.
mRNA cancer vaccine?
MRNA vaccines are also explored to other diseases, including cancer that is difficult to treat.
Pancreatic cancer has a high mortality rate. Nine out of 10 patients do not survive. But US researchers are studying vaccines that can prevent cancer from returning when the initial tumor is removed surgically.
In recent phase 1 clinical trials, in some patients, the vaccine has activated tumor-specific immune cells that remain in the body for up to four years after treatment.
Pancreatic cancer vaccines under development in cooperation between BionTech and US Company Genentech had to be personalized for each exam. It allows the cells in the body to generate Neoantigens, a particular protein found in the tumor of the patient. This trains the immune system to recognize it as a foreigner who needs to fight cancer cells.
The shot is still being developed. The results of the test were published in the natural journal. February 2025.
If the United States stops all federal funds for MRNA research, it’s not clear how much development like cancer or malaria vaccines will continue.
Edit: Matthew Ward AGIUS
