Kilmer S. McCully, a pathologist at Harvard Medical School in the 1960s, claimed that his colleagues were expelled to the basement, claiming that Amino acid, Homo Sista, died in his house in Mass Winchester on February 21.
His daughter, Martha McCully, said the cause is metastatic prostate cancer. His death was not widely reported at the time.
Today, Dr. Mac Curley’s theory, which is still controversial, was to strengthen the artery with plaque by causing a high -level homocysteine in the blood due to the inappropriate intake of certain B vitamins. The idea has challenged the cholesterol -centered paradigm supported by the pharmaceutical industry.
Dr. McCully didn’t think cholesterol should be ignored, but I thought it was negligence to ignore the importance of Homo Sistine. Harvard’s boss did not agree. First, they moved the laboratory below the ground. Then they told him to leave. He struggled to find work for several years.
He told Ki and Colata, the New York Times medical journalist in 1995, “This was very traumatic.”
Dr. MCCULLY created himself as a microorganism hunter similar to Luis Pasteur and accidentally found Homocysteine at a medical conference in Boston in the late 1960s. There he learned Homo SistineGenetic diseases in which a large amount of homocysteine is found in the urine of some developmental disabilities.
Doctors suggested the case of a nine -year -old girl’s homosist urinary, and mentioned that her uncle died in a stroke in the 1930s, saying she was eight years old in the 1930s and had the same disease. “How did an 8 -year -old child die in the way old people do?” Dr. McCully wrote with his daughter in the Heart Revolution (1999).
He was surprised when Dr. McCully tracked autopsy reports and tissue samples. The boy strengthened the arteries, but there was no cholesterol or fat in the plaque accumulation. A few months later, he learned about a baby with a recent death of Homo Sistine. He also strengthened the arteries.
“I slept for two weeks,” he wrote.
In 1969, Dr. McCully published a paper on the case of American Journal of Pathology. In the same journal next year, he explained what happened after injecting a rabbit with a high dose of homocysteine. “The aorta of all 13 animals that injected Homo Stein became moderately thick,” he wrote.
Dr. McCully tracked another study. He suggested that people with low folic acid and vitamins B6 and B12 should consume five servings of fruits and vegetables a day. He also recommended the development of blood tests for homosysteine.
Dr. MCCULY told The Times that a medical expert responded to “Stony Silence.” He told him in 1979, “I think we did not prove your theory.” He decided to leave and unemployed until 1981 until the Veterans Secretariat in RI’s Providence hired him as a pathology.
J. David Spence, an honorary professor at the University of Western Ontario, studying Homocysteine, said in an interview, “I felt for him and admired him.” He neglected more than he did. sad.”
In the early 1990s, a large -scale long -term study on the risk of heart disease showed that Dr. McCULLY is actually heading the right way when Harvard has demoted him to the basement.
. Data Framing Ham Heart StudyStarting in 1948, it was still carried out, and the ratio of curing arteries connected to the brain was high among the participants who had a high level of homosysteine. According to a study by Harvard Public Health School and Boston’s Brigham and Women’s Hospital, men with high homo -sized men are three times more likely to have a heart attack than a low -level man.
“At the end of the day, he was right in the sense that Homocystein was a marker that could have a high risk of cardiovascular disease.” Meir Stampfer, Harvard infectious scholars said in an interview by a Harvard epidemic specialist who led the study. “He gets credit for helping to develop this theory and provide evidence.”
Kilmer Serjus McCully was born on December 23, 1933 in NEB. Harold McCully was a psychological counseling expert in the US Department of Education. His mother Lulu (Litwinenco) MCCULLY was an artist and piano teacher.
In his teenagers, Kilmer was fascinated by Paul de KruiF’s 1926 book “Microbe Hunters” on Pastur, Walter Reed, Robert Koch and other people who surveyed the epidemics. He almost knew he wanted to be a scientist immediately.
He studied biochemistry, psychology, and chemistry in Harvard, taught with psychologist BF skinners, and graduated to friends known as Kim in 1955.
Dr. MCCULLY joined the Harvard Medical College of Pathology in 1965, following internships and post -doctoralism at Massachusetts General Hospital.
He married Annina Jacobs in 1955 and died in 2023.
In addition to his daughter Masa, his son Michael survived. Two grandchildren; Two great -grandchildren; And sister Marilyn McCli.
After the 1990s research supported his theory, Dr. McCully became a media star.
New York Times Magazine presented him in the 1997 article in “The Fall and Rise of Kilmer McCully”. In 1999, in the NPR program “Fresh Air” Sayed Host Terry Gross said, “I am very satisfied because I wanted to be with my life when I was a young man.”
However, Homo Sistine remains a controversial topic in medicine.
Major medical organizations did not recommend testing this by quoting the mixing results of the study that investigated whether lowering homocystein led to a decrease in cardiovascular events. (There is more powerful evidence that it can help prevent stroke.)
“It’s a strange business that people still don’t pay attention to this,” Dr. Spence said. “The doctor wouldn’t have liked biochemical classes.”
As for Harvard, Dr. Mac Curley’s family never bitter about his treatment. In 1999, his classmates introduced him as a platter.
“It was engraved with Kim McCully.
