Major kidney transplantation innovation can change how we fight the world’s long -term shortage. Scientists have found a way to convert Type A’s height into a universal donor (O type) and opened the door for faster, safer and more accessible kidney donation in the United States. Cancer and deep sea fat: New research links visceral fat activity with women’s aggressive cancer growth.Lipycondary Alarm: Research discovers the most deadly risk factors of masld patients, a common type of fatty liver disease.This innovation deals with one of the largest barriers of organ transplantation and blood type, which is now waiting for a kidney that is compatible with thousands of patients for years.
More than 90,000 people in the United States alone height Almost half of them have O -type blood, so they face the longest waiting time. By creating universal donors, the doctor can save a lot of lives, reduce the waiting time for several years, and reconstruct the future of kidney donation and transplantation.
Why blood type is important in kidney transplantation
The blood type determines whether the body accepts or rejects organs. The important reason is:
- Blood cells and long -term antigens (small markers) determine the blood type.
- If the blood type receives a different kidney, the immune system can attack and reject.
- Type O kidney is said to be universal donors because there are no major antigens. In other words, anyone can be transplanted to anyone.
- O-type blood patients often wait for the kidneys for 2-4 years because they are often unacceptable in type A, B or AB.
What did scientists do?
Researchers started with the height of the donor, and converted them to O -type kidney using special enzymes.
- The kidneys have been treated as an enzyme that blocks antigens in charge of blood type A.
- This process effectively “washing” the kidneys and made it look like a type O of the immune system.
- Then I tested the transformed kidney into a brain-guard patient (with family approval) and tested.
Did it work?
For two days, the universal donor height worked normally without refusal. But on the third day, some antigens came back and the patient’s immune system began to attack organs.This means that this technology works temporarily but is not permanent yet. Nevertheless, it is an important concept of concept in the future of American kidney transplantation.“Here, we present a donor-centered desk, and converts the type A kidneys to the enzyme-converted O kidney to remove the A antigen from the kidneys. All of the models in vivo did not cause antibody-mediated damage. The researchers did not observe antibodies and superiority.”
The reason why this breakthrough is important to the United States
Fast kidney transplantation: A patient, who takes up almost half of everyone, can get a height from more donors.Long -term shortage solution: The universal donor height can significantly reduce the list of waiting.More safer transplantation: The patient does not need dangerous treatment to withstand the inconsistency.
Process
- Enzyme perfusion: The donor is soaked in the solution with the enzyme for about 2 hours.
- Remove antigen: Enzymes block antigens that cause rejection.
- Long -term preservation: The kidney is stored using standard transplantation technology until surgery.
Limit and the next step
Antigen removal is not permanent over time, and some are returned.It was only tested in brain-guard prisoners, not still a living patient.Future studies will combine this enzyme process with anti -transplantation that usually use it.
Can it be effective for other organizations?
yes. The same enzyme -based method has already been tested in the lungs in the laboratory environment. Scientists hope to be applied to the heart, liver and lungs in the future.According to this breakthrough kidney transplant study, enzymes can be used to create universal donors in just a few hours. More tests are required, but this can be one of the most important organ transplant innovations in the US troops, potentially saving thousands of lives and ending long -term waiting time for O -type patients.See also: You can eat every day without compromising on the taste and nutrition of kidney health.
