The reader of our synchte newspaper column tells us that we have stopped antihistamines 15 years ago. Zyrtec (Cetirizine) led to an unbearable itching. It wasn’t the first report we received, but it was my first time to write this strange result in our column. We have been cautious about this strange reaction because dermatologists often prescribe such antihistamines. subtend itch. Antihistamine seemed to be contradictory that I could actually do it. cause Itching of withdrawal (chest salt) when stopped.
Snowballs that began the eye of the snow:
The following is the first letter about the withdrawal of Zyrtec we published in the newspaper column.
cue. I had a terrible difficulty trying to stop taking Zyrtec (generic is cetirizine). While taking an allergic shot, I used this antihistamines and first tried to stop the allergic test. In three days, my whole body was itchy. I was so terrible that I was preparing for relief to cry and go to the hospital.
I was confused by constant itching, and I accidentally forgot and took Zyrtec. Purple, the symptoms disappeared before I dressed in clothes and riding a car. Now seven years later, I failed at least 10 times to quit this medicine, and the response is more serious every time.
Today I discovered the community of thousands of people who had the same problem as me while studying this problem online. There must be a better warning about this withdrawal problem.
Hundreds of people stopped Zyrtec and reported withdrawal.
Our surprisingly, readers from all over the country responded to the other newspaper columns we wrote about the terrible systemic itching, which was nominated for cetirizine. Others wrote that the same thing happened to them after the relevant antihistamines and Levose Tyricin.xyzal).
We contacted the Food and Drug Administration as often when new or unusual side effects occur. At first, we did not listen again. It is quite common of the FDA. But we do not give up easily.
We continued to write about withdrawal that related to cetirizine and levocetirzine. Here are some of the articles posted on the newspaper column and this website.
Itching that does not end | Itching after stopping Xyzal (Levocetirazine)
Zyrtec itch is impossible | Where is the FDA?
Unbearable itching after stopping antihistamines such as Xyzal or Zyrtec
You get an idea. We were constantly. We nagged the FDA for several years on this problem.
The FDA responds to withdrawal on June 3, 2018.
Surprisingly, the FDA finally admitted that there could be a problem.
“FDA website ‘Potential signals for serious risks/new safety information is the FDA side effect reporting system reporting system Faers’Cetirizine, Levocetirizine and Hydroxyzine. Induced the evaluation to decide.
“As a result of this review, prescription libocetirizine prescription information has been modified to include the following information about Pruritus after stopping cetirizine in side effects-side effects-post marketing experience sections.”
We were happy to find this article in the medical literature of the FDA investigator. The institution has found more than 100 cases in the FDA side effect report system reporting system (Faers) database.Drug safety treatment developmentJuly 5, 2019). The title of the article is as follows:
“Itching after cetirizine interruption ”
We did not achieve much success and searched for low labeling. We were particularly disappointed that there was no mention of withdrawal of withdrawal of cetirizine or libocetirizine OTC labels. In this link, you can read a message to Dr. Gerald Dal PAN. Dr. Dal PAN has been a major position in the FDA for many years, including: Director of Pharmaceutical Safety Bureau, Surveillance and Epidemiology Director and Pharmaceutical Evaluation Office II.
A new presentation of FDA’s withdrawal of withdrawal:
On May 16, 2025, the agency issued “FDA drug safety communication”.
We are not sure how rare this problem is. In the case of withdrawal itch reported on this website, we will speculate that this side effect may not be as rare as the FDA thinks. Nevertheless, 15 years later, the agency is pleased to need to change the label for “updated prescription information” and OTC packaging.
“What is the FDA doing?
“We are adding warnings about the risk of itching after stopping the long -term use of prescription cetirizine. Or in Levocetirizine Prescription information To raise awareness of this rare but serious reaction. The updated prescription information also has symptoms of itching. Restart the medicine. We will also ask the manufacturer to add a warning to Pruritus. Drug facts label OTC Cetirizine and Levocetirizine. In the meantime, we want to make the public I know this danger. If additional information is provided, we will take subsequent measures. ”
What should doctors and patients do about withdrawal?
Surprisingly, the FDA does not provide much useful information about drug interruptions such as Zyrtec or Xyzal or a common Seti rygin or levocetirizine.
“What should the patient and parents/caregivers do?
“If serious itch occurs after stopping, the patient must contact a health care professional. Prescription or OTC Cetirizine or Levocetirizine. Patients should know that itching generally occurred. In a few days after stopping this medicine after a few months and several years. individual Long -term use plan for cetirizine or libocetirizine, especially for months Discuss the benefits and risks with your medical experts. Personal needs.
“What should a medical expert do?
“Health care experts should discuss the risk of Pruritus after stopping cetirizine or levocetirizine. When prescribing or recommending this medicine, patients, especially plans for chronic use And with people who indicate that they are using the OTC version. Encourage the patient to contact if the patient contacts After stopping Seti Rijin or Leva’s three Tyricin, experience serious itch. Effective treatment for itching It was not evaluated. However, symptoms have been resolved in most patients who have restarted the medicine. And for those who thinner after starting it again. ”
One option that the FDA suggests itching is to restart the antihistamines. It is similar to talking to someone who wants to stop taking benzodiazepine, such as Alfra Zolam.Xanax), antidepressants such as enlafaxine (Effexor) Or acidic drugs such as omeprazole (PRILOSEC) If the withdrawal symptoms occur after the drug is discontinued, the drug resumes. I am less than satisfying that advice.
Final word:
I am very happy to find that FDA admitted that itching could occur when people stop taking drugs such as Seti Rijin or Levoseti Rijin. It took a long time, but the FDA rich suggested that the new drug safety communication is the result of our efforts. This individual thanked him for “advocating the patient and promoting the FDA to take action.” It means terrible.
We think that this reaction can be more common than the FDA thinks. Hundreds of readers suggest that people can successfully escape such antihistamines by suggesting a very gradual taper for several weeks or months.
Scrolling to the top of this article will appear a search window. You can find many articles you can choose by putting cetirizine itch, zyrtec itch, or xyzal itch in the search box. The readers shared various strategies to stop these drugs in the opinion section of the article.
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