Do you like Ozempic and drugs? cant do? Today’s study shows that GLP-1 drugs often increase male testosterone.
Scientists from St. Lewis, Missouri, led this study, which studied men taking one of several GLP-1 drugs for type 2 diabetes and obesity. On average, male testosterone has risen significantly after taking GLP-1, and many reached normal levels. Research results show that these weight loss drugs can have the benefits of reproductive health for men, researchers say.
Testosterone is important for the health of men and women, but especially for the former. For men, we specify some functions by maintaining muscle mass, bone density and reproduction. Those who develop type 2 diabetes or obesity often experience T -level reduction. On the contrary, people who control weight loss or blood sugar recovery This lost testosterone.
However, there are not many studies about what happens to men and testosterone when you start taking GLP-1, such as Semaglutide (active ingredient of diabetic drugs and obesity drugs). And they wanted to better understand the wider health benefits of these drugs in addition to weight loss.
The team analyzed more than 200 men with a type 2 diabetes or obesity prescribed for GLP-1 (Semaglutide, Tirzepatide or Old GLP-1 Dulaglutide) and analyzed a person who did not add testosterone or other hormones.
Men’s blood sugar control and weight have increased by 10%and testosterone as expected. The average male average and free testosterone levels have noticeably risen from the baseline. Only 53%of men had a normal T level before GLP-1 treatment; The same was true for 77%of men. The team’s discovery was presented at the annual meeting of the Endocrine Association on Monday.
The T-boosting effect of GLP-1 therapy was not as big as it can be seen in other weight loss treatment, especially in surgery. However, the drug provides its own advantages, according to the senior researcher at the Shellsea Portillo Canales.
SSM Health St. Portillo Canales, a endocrine researcher at Louis University Hospital, said to Gizmodo, “It’s less dramatic than the rise after obesity.” However, the advantage of GLP-1 is non-invasive and accessible, especially when combined with weight loss, it can naturally improve testosterone when combined with weight loss. It is. “
Improvement of male testosterone levels has correlated with how many pounds they spilled, suggesting that weight loss is the main driver of this effect. However, Portillo Canales does not exclude that other factors such as improved insulin resistance and low inflammation are also important.
Researchers want to further check this link through the prospective study of tracking men and testosterone levels in advance in GLP-1 therapy. But given that these patients are already taking these drugs for diabetes or obesity, the potential improvement of testosterone can be seen as a great bonus. Still be careful. Portillo canales point out that men can go back with testosterone levels if men stop taking GLP-1 and start gaining weight.
