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Brown fat tissues can help to promote healthy longevity and maintain aging’s athletic ability.
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Brown fat tissues can help to promote healthy longevity and maintain aging’s athletic ability.

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Rutgers Health researchers have found a brown region that can open a new way to help people stay healthy as they age.

A team of Rutgers New Jersey Medical School found that a mouse without certain genes has developed an abnormally strong brown tissue that expands its lifespan and increases athletic ability by about 30%. The team is studying drugs that can imitate this effect on humans.

Stephen Vatner, a university professor and director of the Cardiovascular Research Institute of Catholic Cell Biology and Molecular Medicine, said, “It will be very beneficial to have a technology to reduce your athletic ability and improve your athletic performance as you get older.” study ~ Aging cell. “This mouse model performs better than normal feces.”

Unlike white fat that stores energy, brown fat helps to burn calories and control body temperature. This study revealed that brown fat plays an important role in motor skills by improving blood flow to muscles during physical activity.

Genetic modified mice produced abnormally high amounts of active brown fat and showed about 30% more exercise performance than normal mice in both speed and exhaustion time.

This discovery came out of healthy aging in a wide range of studies. The modified mouse without protein called RGS14 lives about 20% longer than the normal mouse, and the female lives longer than men. Even in advanced ages, they maintain a healthier appearance, avoiding typical aging signs such as loss and gray in normal elderly mice.

Their brown fat tissue also protects them from obesity, glucose intolerance, cardiovascular disorders, cancer and Alzheimer’s disease.

In order to test whether brown fat gained the benefits of the missing genes, researchers transplanted brown fat into the normal mouse. They mentioned that the recipient had similar benefits in a few days. In contrast, transplantation using a common brown fat from the normal mouse took eight weeks to improve much lighter.

This discovery can eventually improve human life. It is a total time for people to enjoy good mental and physical health.

Vatner said, “All medical development has increased human aging and lifespan, but unfortunately it is not aging.” “There are many diseases related to aging such as audiences, diabetes, myocardial ischemia, heart failure, cancer, and what we need to do is to find new drugs based on health aging models.”

Vatner said his team plans to test certain benefits such as athletic ability and metabolism. This approach is based on previous success in drug development based on other mouse healthy longevity models.

“We are developing this agent in cooperation with some people, and we will have drugs we can test for about a year.”

In the meantime, technologies such as deliberately cold exposure can naturally increase brown fat. Studies have found that efforts have been made to produce short -term benefits, from improved immune system functions to improved metabolic health, but Vatner has not been executed for a long time to affect the aging of health.

He added that most people prefer to take medicine instead of ice bathtubs to raise brown fat levels, and are optimistic about translating the latest discoveries into effective drugs.

Additional information:
Dorothy E. Vatner et al, brown fat tissue improves kinetic performance and healthy longevity. aging (2024). Doi: 10.18632/Aging.206179

Provided by Rutgers University


recall: Brown regional organizations can help to promote healthy longevity and maintain aging’s athletic ability (March 4, 2025) March 4, 2025

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